What special precautions should I follow?
Before taking ketolides (telithromycin):
Tell your doctor if you have ever had an allergic reaction to other antibiotics such as erythromycin (Ery-Tab®, E.E.S.®, PCE®, Erythrocin®), azithromycin (Zithromax®), clarithromycin (Biaxin®), troleandomycin (TAO®), or dirithromycin (Dynabac®).
Please inform your doctor if you have kidney disease, liver disease or a history of liver problems caused by telithromycin, myasthenia gravis (a neuromuscular disorder), low levels of potassium in the blood (hypokalemia), low levels of magnesium in the blood (hypomagnesemia), a heart rhythm disorder, or a family history of Long-QT syndrome.
Furthermore, tell your doctor if you are also using any of the following drugs: cholesterol-lowering medicine such as simvastatin (Zocor®), lovastatin (Mevacor®), atorvastatin (Lipitor®); ergot medicine such as ergotamine (Cafatine®, Cafergot®), dihydroergotamine (Migranal®, D.H.E. 45®); a sedative such as diazepam (Valium®), midazolam (Versed®), alprazolam (Xanax®), chlordiazepoxide (Librium®), temazepam (Restoril®); itraconazole (Sporanox®) or ketoconazole (Nizoral®); heart rhythm medication such as amiodarone (Cordarone®, Pacerone®), sotalol (Betapace®, Betapace AF®, Sorine®), quinidine (Cardioquin®, Quinaglute®), disopyramide (Norpace®), procainamide (Pronestyl®, Procanbid®), dofetilide (Tikosyn®); rifampin (Rifadin®, Rimactane®); seizure medication such as phenytoin (Dilantin®), carbamazepine (Tegretol®), phenobarbital (Luminal®); metoprolol (Lopressor®, Toprol XL®); tacrolimus (Prograf®) or sirolimus (Rapamune®); cyclosporine (Sandimmune®, Neoral®); or digoxin (Lanoxin®, Lanoxicaps®); cisapride (Propulsid®) or pimozide (Orap®).
If you have any of the conditions listed above, you may not be able to use this medicine or you may need a dosage adjustment or special tests during treatment.
Telithromycin is in the FDA pregnancy category C. This means that it is not known if it will be harmful to an unborn baby. Do not use this medication without telling your doctor if you are pregnant. Tell your doctor if you become pregnant during treatment.
So too, it is not known whether telithromycin passes into breast milk. Do not take this medication without telling your doctor if you are breast-feeding a baby.
Why is this medication prescribed?
Dosage and using this medicine
What should I do if I forget a dose?
What side effects can this medication cause?